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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMPH All Species: 40
Human Site: Y63 Identified Species: 97.78
UniProt: P49418 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49418 NP_001626.1 695 76257 Y63 L Q R E L R G Y L A A I K G M
Chimpanzee Pan troglodytes XP_519055 930 101395 Y166 L Q R E L R G Y L A A I K G M
Rhesus Macaque Macaca mulatta XP_001100126 694 76130 Y63 L Q R E L R G Y L A A I K G M
Dog Lupus familis XP_533085 836 91248 Y79 L Q R E L R G Y L A A I K G M
Cat Felis silvestris
Mouse Mus musculus Q7TQF7 686 74995 Y63 L Q R E L R G Y L A A I K G M
Rat Rattus norvegicus O08838 683 74859 Y63 L Q R E L R G Y L A A I K G M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516791 687 75140 Y63 L Q R E L R G Y L A A I K G M
Chicken Gallus gallus P50478 682 75187 Y63 L Q R E L R A Y L A A I K G M
Frog Xenopus laevis NP_001085079 666 74474 Y67 L Q R E M R A Y L A A I K G M
Zebra Danio Brachydanio rerio NP_957125 784 85747 Y63 L Q R E M K A Y I A A V K G M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.7 97.4 63 N.A. 85.1 86.4 N.A. 74.9 72 61.4 50.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 73 98.2 68.6 N.A. 88 89 N.A. 82.3 80.5 71.6 64.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 86.6 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 93.3 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 30 0 0 100 100 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 70 0 0 0 0 0 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 90 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 0 0 100 0 0 % K
% Leu: 100 0 0 0 80 0 0 0 90 0 0 0 0 0 0 % L
% Met: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 100 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 100 0 0 90 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _